Immunotherapy
Most effect treatment for Hayfever
Immunotherapy is a treatment used to alleviate the persistent symptoms caused by specific allergens. It is created using modified allergens, known as extracts. Allergic reactions occur when allergens, such as grass or tree pollen, dust mites, or animal danders, come into contact with antibodies called IgE in individuals with allergies. The interaction between the allergen and the antibody triggers the release of chemicals such as histamines from allergy cells called mast cells, resulting in symptoms like itching, sneezing, swelling, and wheezing.
Traditional allergy medications work by managing symptoms after an allergic reaction has occurred. However, in some cases, these medications may not be effective in controlling symptoms. Immunotherapy can be used as an alternative in these situations, as it aims to change the way the immune system reacts to allergens. This is achieved by producing blocking antibodies called IgG, which can prevent the reaction between the allergen and IgE and stop the allergic reaction from occurring.
Immunotherapy is available for hay fever caused by grass and tree pollen, allergic rhinitis caused by dust mites, and severe allergies to horses, cats, and dogs. There is a significant amount of research and many years of experience that support the use of immunotherapy to reduce the symptoms of allergic rhinitis caused by grass pollen, tree pollen, and dust mites that are resistant to traditional allergy medications.
You will be considered for Immunotherapy treatment if you:
- Do not have a long-term infectious condition (e.g. HIV, tuberculosis )
- Are not on any of the following medications (Immunosuppressants, Beta Blockers)
- Have not ever had a serious allergic reaction or “Anaphylaxis”
- Have not been diagnosed with an autoimmune condition (e.g., thyroid, vitiligo, rheumatoid arthritis, Crohn’s or ulcerative colitis)
- Are not currently undergoing active treatment for cancer like chemotherapy/ immunotherapy
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Your Benefit
Common Hayfever Symptoms
Itchy/Blocked/Runny nose
Sneezing & Coughing
Itchy/Red /Watery eyes
Low Concentration
Tired/ Worn out
Generally unwell
Headache
Seasonal Asthma
Frequently Asked Questions
We have compiled a list of common FAQs for your reference
Sublingual immunotherapy involves placing an allergen extract under the tongue, either as spray or drops.
Subcutaneous Immunotherapy involves having a series of injections over a period of three to five years. Due to the availability of safe oral options, injection immunotherapy is rarely needed.
The specific product used for your treatment will be determined based on your clinical history and results from allergy testing. Typically, treatment begins a few months prior to the typical onset of symptoms (if the allergy is related to pollen) and is continued for a period of three years.
Because SLIT works by altering the immune system, its benefits would be expected to continue even after the treatment is completed. Studies have also shown that it may decrease the likelihood of developing new allergies and asthma.
Immunotherapy is the only treatment option that can address the root cause of an allergy, while alternative treatments such as antihistamines and steroid-based medications can only alleviate symptoms but do not address the underlying cause. Furthermore, they may come with potential side effects. Immunotherapy involves the gradual exposure to increasing amounts of the allergen, which can lead to a decrease in sensitivity and symptoms over time, and can also decrease the need for symptom-relieving medication
Sublingual Immunotherapy (SLIT) has been found to be an effective treatment option for hay fever. Studies have shown that 80-85% of patients who undergo SLIT for hay fever report significant improvement in their symptoms during the first year of treatment, and this improvement tends to continue throughout the treatment period and decreasing the need for medication to manage allergies.
Sublingual immunotherapy (SLIT) is a form of treatment that has been found to be effective in improving symptoms of allergies and reducing the need for traditional treatments, such as antihistamines and steroid nasal sprays. This treatment approach can help to build up a patient’s tolerance to allergens by administering small doses of the allergen under the tongue. Additionally, SLIT may prevent the development of new allergies and decrease the risk of asthma.
This type of treatment may be beneficial for individuals who:
- Seek a long-term solution for their allergies
- Cannot avoid their allergy triggers (e.g. pollen, dust, pets)
- Experience side effects or reduced effectiveness from allergy medication
- Wish to decrease their medication use
- Have allergic asthma and wish to decrease their use of asthma medication.
SLIT is considered a safe and effective treatment option for allergies and it’s a convenient way of administering the treatment as it can be done at home. It’s a good alternative for those who can’t tolerate or don’t respond well to traditional methods
Sublingual immunotherapy (SLIT) is a treatment option that is typically recommended for individuals whose allergy symptoms are not well-controlled by standard medications and are impacting their quality of life and daily functioning such as socialising, working, or sleeping.
Sublingual immunotherapy (SLIT) is considered a safe and effective treatment option for allergies, with a low risk of severe reactions. In 1998, the World Health Organization (WHO) recognized SLIT as a viable alternative to injection therapy, and its use in clinical practice is widely accepted.
Multiple studies from around the world have confirmed the safety of SLIT for the treatment of rhinitis and asthma caused by allergies to dust mites, grass, ragweed, cat dander, and tree pollens. Severe reactions are uncommon, and side effects are usually mild and temporary.
SLIT is safe for both adults and children, as confirmed by numerous studies over the past decade. The WHO has endorsed SLIT as a safe and effective alternative to injection therapy, making it a viable treatment option for patients of all ages.
It is important to note that access to sublingual immunotherapy (SLIT) on the National Health Service (NHS) in the UK is currently very limited and not available in most areas. If you are interested in exploring this treatment option, it is recommended to discuss it with your GP or specialist within the NHS. They will be able to advise you on the availability and suitability of SLIT for your specific allergy condition
The cost of sublingual immunotherapy (SLIT) can vary, but on average it is typically around £125-£150 per month.
It is important to follow proper administration guidelines when taking sublingual immunotherapy (SLIT) treatment. After taking the treatment, it is essential to avoid swallowing for the first minute and to not consume any food or drink for five minutes afterwards. This is to ensure that the treatment is properly absorbed under the tongue, and to avoid dilution or neutralisation of the treatment to help optimise the effectiveness of the treatment and ensure the best possible outcome.
Sublingual immunotherapy (SLIT) is generally considered safe and does not affect the ability to drive or operate machinery. However, as with any medical treatment, it is important to consult a doctor if you have any doubts about your ability to do so
Some sublingual immunotherapy products contain a small amount of fish gelatin as an ingredient. Fish gelatin is commonly used as a thickening agent in a variety of food and medical products.
Whilst there is limited research on the effects of sublingual immunotherapy during pregnancy, it is generally recommended to avoid starting the treatment during this time. However, if a patient is already undergoing treatment before becoming pregnant, they can continue the course of therapy with the guidance of a medical professional. Similarly, there is no data available on the effects of sublingual immunotherapy during breastfeeding, but it is not expected to have any negative impact on breastfed babies. Consult with a healthcare provider to determine if sublingual immunotherapy is safe and appropriate for you.
It is important to inform a doctor before starting sublingual immunotherapy if you have any of the following conditions: severe asthma, illnesses that affect the immune system, severe inflammation of the mouth, or cancer. Additionally, special precautions should be taken if you have recently undergone oral surgery or extraction, have a severe fish allergy, or have had an allergic reaction to an injection of grass pollen allergen. These concerns can be discussed during an initial assessment consultation.
Sublingual immunotherapy is generally considered safe and well-tolerated, however, like all medications, it can cause side effects. Common side effects include mouth itching and an irritating sensation in the throat, which usually resolve within 20 minutes of taking the dose. Other common side effects include headache, prickling or numbness of the skin, itching in the eyes or ears, nasal discomfort, and stomach pain or discomfort. These side effects are typically mild and short-lived, but if they are severe or persistent, it is important to consult a doctor.
In rare cases, sublingual immunotherapy can cause more serious side effects such as rapid swelling of the face, mouth or throat, difficulty swallowing or breathing, hives, or worsening of asthma symptoms. If you experience any of these symptoms, stop taking the medication and seek medical attention immediately. It is also important to note that sublingual immunotherapy should not be taken if you have open sores, cuts or ulcers in your mouth or if you are undergoing dental procedures that cause bleeding. You should wait until your mouth has healed before resuming treatment.
It is important to follow the prescribed treatment schedule for sublingual immunotherapy to achieve the best results. Missing a dose may not cause any immediate side effects, but it can lead to a return of allergy symptoms. If you miss a dose, take it as soon as you remember, but do not take a double dose on the same day to make up for missed doses. Consult your doctor or pharmacist if you have any questions or concerns about your treatment schedule.
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